An experimental therapy designed to change a single letter of short-lived mRNA molecules has corrected a genetic mutation ...

Messenger RNA (mRNA) serves as a blueprint for proteins. When mRNA is no longer needed, it must be degraded. Director Elena ...

Scientists have identified the likely geological and environmental conditions that fostered the development of life as we ...

Early trial data of two virally suppressed, breast-feeding women with HIV shows that there may be less of a risk of HIV ...

Victor Ambros and Gary Ruvkun have been awarded the Nobel Prize for their research on microRNA.

MicroRNAs hold particular promise in cancer treatment. Some of these molecular switches act as tumor suppressors, effectively ...

Gary Ruvkun, professor of genetics at Harvard Medical School and an investigator at Massachusetts General Hospital, has ...

The prize was awarded for the discovery of microRNA and “its role in post-transcriptional gene regulation.” MicroRNA plays an ...

In a new book, astrophysicist Mario Livio describes how the existence of life on Earth can be traced back to an RNA-based ...

Proteins that trigger cell senescence occupy much of the literature on aging, but a small RNA moves into the limelight.

Readers should recognize the significance of MDA5 in potentially replacing RIG-I and the adversarial strategy employed by 5'ppp-RNA SCRV in degrading MDA5 mediated by m6A modification in different ...

This important study shows that in teleost fish, the RIG-I-like protein MDA5 can compensate for the absence of RIG-I by detecting 5'-triphosphorylated RNA. A fish virus containing such RNA can ...