EPFL researchers have developed a computational method to explicitly consider the impact of water while designing membrane receptors with enhanced stability and signaling, paving the way for novel ...

Proteins are life's engines, powering processes like muscle movement, vision, and chemical reactions. Their environments—water, lipid membranes, or other condensed phases—are critical to their ...

Adhesion G protein-coupled receptors (GPCRs) are a group of cell-surface sensors associated with many body functions and diseases. However, they are not yet sufficiently understood to be exploited for ...

Receptors and membrane biology are critical areas of study in understanding how cells communicate and interact with their environment. Receptors, particularly G protein-coupled receptors (GPCRs ...

Proteins are life's engines, powering processes like muscle movement, vision, and chemical reactions. Their environments-water, lipid membranes, or other condensed phases-are critical to their ...

Researchers at the Leibniz Institute for Food Systems Biology at the Technical University of Munich have for the first time investigated how protein structures derived from fava beans affect a ...

The same mechanisms involved in COVID-related cardiovascular events are responsible for COVID-related myocarditis.

G protein-coupled receptors (GPCRs ... which leads to their opening and subsequent hyperpolarization of the cell membrane. This process is modulated by various factors, including phosphorylation ...

Researchers at the Leibniz Institute for Food Systems Biology at the Technical University of Munich have for the first time investigated how protein structures derived from fava beans affect a ...

Adhesion GPCRs are a group of cell-surface sensors associated with many body functions and diseases. However, they are not yet sufficiently understood to be exploited for therapies. Scientists have ...

His team then extracted the receptor from the cell membrane and forged an initial understanding of ... This family is now known as G-protein-coupled receptors, and the studies by Lefkowitz and Kobilka ...

Frizzled (FZD) proteins are the principal receptors of the Wnt signaling pathway. However, whether Wnt ligands induce FZD endocytosis and degradation remains elusive. The transmembrane E3 ubiquitin ...