Scleroderma is classified as a rare, autoimmune, collagen-vascular disease of unknown etiology that can be difficult to diagnose and treat. Its onset can be insidious or rapid; the symptoms range ...

Over time, these changes can spread to other body parts, such as the face, arms, or chest. In addition to skin changes, systemic scleroderma can cause other symptoms such as joint and muscle pain ...

UK: A recent systematic review published in Clinical Rheumatology has investigated the potential of botulinum toxin (BTX) as ...

The signs and symptoms of scleroderma can be mistaken for any number of diseases, depending on the predominant symptom at the time of examination. Numerous referrals to specialists result in ...