The record for most wins by a wild-card team will be reset as the loser of the Vikings-Lions game Sunday night will hold the new standard.

Quarterback Brock Purdy will not be available to play in the 49ers’ season finale against the Arizona Cardinals on Sunday.

Never before in NFL history have two teams with at least 14 wins each gotten together for a regular-season matchup. But that ...

Baltimore and Pittsburgh will play separate home games Saturday to decide the AFC North. The regular season ends with ...

The San Francisco 49ers came out swinging against the Detroit Lions in Week 17, taking a 21-13 lead into halftime. However, the Lions pounced in the second half, putting up 27 points to complete a ...

Jennifer Lee Chan shares the latest injury report for Sunday's San Francisco 49ers vs. Arizona Cardinals game.

San Francisco 49ers quarterback Brock Purdy exited Monday night's shootout with the Detroit Lions in the final two minutes, as the Niners were driving for a late touchdown to cut the Lions' lead to ...

The Seahawks hit the road for the final time this season as they get set to take on the division rival L.A. Rams in Week 18. Seahawks reporter Jen Mueller breaks down the Seahawks' final game of the ...

Check out the latest injury report for the 49ers, including Deebo Samuel's status ahead of the Week 18 showdown against the Cardinals.

Nick Khan's prediction becomes a reality on Monday night. The World Wrestling Entertainment executive said during earning ...

Former Pittsburgh Steelers quarterback Josh Dobbs will start for the San Francisco 49ers in their game against the Arizona ...

Darnold signed a one-year deal worth $10 million to join the Vikings ahead of this season. Last week, Spotrac projected his ...