The American Association for Cancer Research Annual Meeting 2025 will be held from April 25-30 in Chicago, Illinois, providing a ...

Stochastic modelling is the development of mathematical models for non-deterministic physical systems, which can adopt many possible behaviours starting from any given initial condition.

Bright expression in hematopoiesis. Hematopoietic progenitor populations ... Schematic diagrams of fragments including the Eμ core enhancer show binding site for E proteins, Ets proteins (μA, μB, HE2) ...

Clonal hematopoiesis (CH) has been associated with a variety of adverse outcomes, most notably hematologic malignancy and ischemic cardiovascular disease. A series of recent studies also suggest that ...

Researchers find that certain antioxidant enzymes, called selenoproteins, significantly contribute to fighting cell aging. The team used a gene knockout mouse model to help them study the effects of ...

This valuable study presents a mouse gastruloid model that can be used to generate hematopoietic progenitors as well as leukemic cells. However, in its current form, the manuscript is inadequate ...

Megakaryocytes form a three-dimensional (3D) cage composed of laminin and collagen IV connected to the basement membrane surrounding them. This microarchitecture stabilizes megakaryocytes within their ...

The following represents disclosure information provided by authors of this manuscript. All relationships are considered compensated unless otherwise noted. Relationships are self-held unless noted. I ...

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I believe this new technology represents a major advance that will open many doors for us as we continue our efforts to probe, understand and modulate the inner workings of human hematopoiesis and ...