The Cincinnati Bengals will try to do something Saturday night at Pittsburgh that they haven't done since 1995.

The Detroit Lions have revenge on their minds in a road game against the San Francisco 49ers. We give you the latest game ...

The stakes were significantly higher the last time the Detroit Lions and San Francisco 49ers met at Levi's Stadium. However, the Week 17 clash on Monday Night F ...

The Lions-Vikings finale will also feature the most combined wins in a regular-season game in NFL history, per Elias Sports.

SAN FRANCISCO (WNEM) - The Detroit Lions are in San Francisco to take on the 49ers for Monday Night Football. Kickoff is set for 8:15 p.m. The Lions are still fighting for the No. 1 seed in the NFC, ...

Football kicks off tonight at 8:15 p.m. EST as the 6-9 San Francisco 49ers host the 13-2 Detroit Lions at Levi’s Stadium. The ...

You can listen to the 49ers vs. Lions live on SiriusXM. Coverage will be available on channels 225 (49ers) and 226 (Lions).

Here are the two critical matchups to watch on MNF between Detroit Lions and San Francisco 49ers in Week 17, including Penei ...