The work presented will be of interest to cancer biologists and more broadly to those interested in NSCLC translational studies. Non-small cell lung cancer (NSCLC) is the most common subtype of lung ...

PH-894: Potent and Specific Silencing of BRD4 in NK CellsMarlborough, Massachusetts--( - October 16, 2024) - Phio ...

Investigators say adding RNA interference (RNAi) therapy to current treatment modalities may improve outcomes in patients ...

Researchers at the University of Toronto and its hospital partners have developed a method for co-delivering therapeutic RNA ...

The strategy they used, and the pathway they identified ... is cut into smaller fragments called small interfering RNA, or siRNA. These fragments are used to block the production of proteins ...

"This could be a game-changer for treating complex conditions where targeting multiple pathways is beneficial, such as cancer and viral infections." siRNA is a powerful tool in medicine, capable of ...

To identify candidates with synthetic lethal effects of CDK12, the authors performed small-interfering ribonucleic acid (siRNA ... the protein kinase B (AKT) pathway. The CDK12/13 inhibitors ...

Eli Lilly and Company (Lilly) focused on advancing potential new medicines for metabolic diseases, including metabolic dysfunction-associated steatotic liver disease (MASLD), based on targets ...

Dharmacon–Thermo Fisher in Lafayette, Colorado, USA, now offers over 51 different siRNA libraries targeting a wide variety of genes and pathways within the human genome, including membrane ...

A high density of tumor-associated macrophages (TAMs) is associated with poorer prognosis and survival in breast cancer patients. Recent studies have shown that lipid accumulation in TAMs can promote ...