PH-894: Potent and Specific Silencing of BRD4 in NK CellsMarlborough, Massachusetts--( - October 16, 2024) - Phio ...

Investigators say adding RNA interference (RNAi) therapy to current treatment modalities may improve outcomes in patients ...

Program for Cancer and Cell Biology, Department of Human Anatomy, Histology and Embryology, School of Basic Medical Sciences; Peking University International Cancer Institute; and State Key Laboratory ...

The work presented will be of interest to cancer biologists and more broadly to those interested in NSCLC translational studies. Non-small cell lung cancer (NSCLC) is the most common subtype of lung ...

It is a serine/threonine kinase that is an essential part of the MAP kinase signal transduction pathway. MAPK1 is involved in a variety of cellular processes, including proliferation, differentiation, ...

Researchers at the University of Toronto and its hospital partners have developed a method for co-delivering therapeutic RNA ...

“This could be a game-changer for treating complex conditions where targeting multiple pathways is beneficial, such as cancer and viral infections.” siRNA is a powerful tool in medicine, capable of ...

The method also allows for the generation of various types of embeddings, including well-level, gene-level, and pathway-level embeddings, which can be derived from transcriptomic profiles, phenomic ...

The strategy they used, and the pathway they identified ... is cut into smaller fragments called small interfering RNA, or siRNA. These fragments are used to block the production of proteins ...

These genes operate in what’s called the RNA interference pathway. Genetic information in cells is converted from DNA into RNA, and then into proteins. Sometimes, double-stranded RNA is cut into ...