gut.bmj2d
Accuracy of histopathology evaluation in diminutive colonic polyps diagnosed as neoplastic by computer-aided characterisation
The removal of colorectal polyps followed by histological evaluation is the current standard of care. Intracolonoscopy ...
gut.bmj18h
Dietary modulation of peroxisome proliferator-activated receptor gamma
Peroxisome proliferator-activated receptor gamma (PPARγ) is a nuclear receptor that regulates intestinal inflammation. PPARγ is highly expressed in the colon and can be activated by various dietary ...
gut.bmj22h
IDDF2024-ABS-0118 Preliminary study on houttuynia cordata-derived exosome-like nanovesicles ameliorating experimental colitis
Background Plant-derived exosome-like nanoparticles (PELNs) have been considered to have great prospects in the treatment of ulcerative colitis (UC) as they serve as a natural nano-drug carrier that ...
gut.bmj1d
Prevertebral ganglia and intestinofugal afferent neurones
Department of Physiology and Biophysics, Mayo Clinic and Mayo Foundation, Rochester, Minnesota, 55905 USA Correspondence to: Dr J H Szurszewski, Department of Physiology and Biophysics, Mayo Clinic ...
gut.bmj1d
Immunoglobulin A–specific deficiency induces spontaneous inflammation specifically in the ileum
Objective Although immunoglobulin A (IgA) is abundantly expressed in the gut and known to be an important component of mucosal barriers against luminal pathogens, its precise function remains unclear.
gut.bmj8d
British Society of Gastroenterology (BSG) guidelines for management of autoimmune hepatitis
Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease which, if untreated, often leads to cirrhosis, liver failure and death. Major advances were made in its management based on ...
gut.bmj4d
Depression in individuals who subsequently develop inflammatory bowel disease: a population-based nested case–control study
Correspondence to Dr Richard C Pollok, Gastroenterology, St George's University Hospitals NHS Foundation Trust, London SW17 0QT, UK; richard.pollok{at}nhs.net Objective Depression is a potential risk ...
gut.bmj9d
The role of gut microbiota in cancer treatment: friend or foe?
Correspondence to Dr Jun Yu, Institute of Digestive Disease and The Department of Medicine and Therapeutics, Chinese University of Hong Kong, New Territories, Hong Kong; junyu{at}cuhk.edu.hk The gut ...
gut.bmj9d
Proton pump inhibitors alter gut microbiota by promoting oral microbiota translocation: a prospective interventional study
Background The mechanism by which proton pump inhibitors (PPIs) alter gut microbiota remains to be elucidated. We aimed to learn whether PPI induced gut microbiota alterations by promoting oral ...
gut.bmj9d
Epidemiology of chronic liver diseases in the USA in the past three decades
Objective Given significant advances in treatment of viral hepatitis and the growing epidemic of obesity, the burden of the different types of liver diseases in the USA may be changing. Our aim was to ...
gut.bmj7d
Location-specific cell identity rather than exposure to GI microbiota defines many innate immune signalling cascades in the gut epithelium
Objective The epithelial layer of the GI tract is equipped with innate immune receptors to sense invading pathogens. Dysregulation in innate immune signalling pathways is associated with severe ...
gut.bmj9d
Increasing butyrate concentration in the distal colon by accelerating intestinal transit
Background—Populations at low risk of colonic cancer consume large amounts of fibre and starch and pass acid, bulky stools. One short chain fatty acid (SCFA), butyrate, is the colon’s main energy ...