He had a history of atrial fibrillation (AF) that initially occurred 2 years before in the context of streptococcal ...

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Mitochondrial dysfunction is a key factor in the development of atherogenesis. METTL4 (methyltransferase-like protein 4) mediates N6- methyldeoxyadenosine (6mA) of mammalian mitochondrial DNA (mtDNA).

Our understanding of hypertension and the ability to lower blood pressure (BP) with pharmacotherapy advanced immensely during the second half of the 20th century and the early 21st century. However, ...

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Our vision is to innovate and incorporate promising technologies to communicate freely available, high-priority, high-quality content, which accelerates scientific progress and advances heart and ...

The policy of American Heart Association journals is to publish papers where authors indicate whether the data, methods used in the analysis (eg, program code or scripts for statistical packages), and ...

Cardiovascular Division and Robert M. Berne Cardiovascular Research Center, University of Virginia, Charlottesville. For Sources of Funding and Disclosures, see page ...

Pulsed field ablation (PFA) has gained attention in cardiac electrophysiology, but data on its application to paroxysmal supraventricular tachycardia are limited. This study aimed to assess the ...

Heart failure with preserved ejection fraction (HFpEF) is a major public health problem characterized by multiple simultaneous comorbidities whose specific contribution is challenging to disentangle ...

Myocardial infarction (MI) is a complex disease caused by both lifestyle and genetic factors. This study aims to investigate the predictive value of genetic risk, in addition to traditional ...

Heart failure with preserved ejection fraction (HFpEF) is a major health concern. Pathological stimuli and interactions between cardiac fibroblasts (CFs) and other cell types may lead to cardiac ...