The EMBO Journal5d
Partitioning of fatty acids between membrane and storage lipids controls ER membrane expansion
PDAT enzymes use membrane phospholipids as direct fatty acid donors to generate triglycerides stored in lipid droplets. This ...
The EMBO Journal5d
Nuclear PD-L1 triggers tumour-associated inflammation upon DNA damage
PD-L1 not only responds to the cGAS-STING pathway upon DNA damage, but also regulates cGAS-STING to induce inflammation. This ...
The EMBO Journal2d
Macrophage-induced enteric neurodegeneration leads to motility impairment during gut inflammation
This study investigates the impact of myenteric neuron-macrophage interactions on postoperative trauma and subsequent ...
The EMBO Journal6d
Viral oncogene EBNALP regulates YY1 DNA binding and alters host 3D genome organization
This month's cover highlights the article A novel bacterial effector protein mediates ER-LD membrane contacts to regulate host lipid droplets by Stacey D. Gilk, Rajendra Angara and Arif Sadi. The ...
The EMBO Journal6d
E3 ligase FBXW7 suppresses brown fat expansion and browning of white fat
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Thermogenic fat, including brown and beige fat ...
The EMBO Journal6d
The dynamics of loss of heterozygosity events in genomes
This month's cover highlights the article A novel bacterial effector protein mediates ER-LD membrane contacts to regulate host lipid droplets by Stacey D. Gilk, Rajendra Angara and Arif Sadi. The ...
The EMBO Journal6d
miRNA-target complementarity in cnidarians resembles its counterpart in plants
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. miRNAs in plants and cnidarian animals operate ...
The EMBO Journal6d
A therapeutic regimen using neoantigen-specific TCR-T cells for HLA-A*2402-positive solid tumors
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The adoptive transfer of TCR-T cells specific ...
The EMBO Journal6d
Hypoxia promotes tumor immune evasion by suppressing MHC-I expression and antigen presentation
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Hypoxia is a common feature of solid tumors ...
The EMBO Journal6d
HDAC6 deacetylates TRIM56 to negatively regulate cGAS-STING-mediated type I interferon responses
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Histone deacetylase HDAC6 has been implicated ...