Researchers at the University of Liège (Belgium) have uncovered a previously unknown mechanism that regulates the immune ...

Finally, PI3K/Akt is a key signaling pathway known to regulate apoptosis in intestinal epithelial cells, and it is expected to explain the mechanism by which Cyn ameliorates intestinal epithelial ...

Chimeric antigen receptor-T (CAR-T) cell therapy, initially successful in hematologic malignancies, presents a promising avenue for treating solid tumors, including CRC. This review explores the ...

A Brock-led research team has discovered a mechanism that provides new insights into stopping the spread of various cancers by controlling a stage of cell signalling, a process through which cells ...

The team said their study showed vast numbers of particles end up absorbed by intestinal cells and, from there, pass into the bloodstream and around the human body. “The biological interaction ...

Here, we introduce cilia-related signalling in head and neck squamous cell carcinoma (HNSCC) and its possible association with HNSCC tumorigenesis. From this point of view, PDGF, EGF, Wnt and Hh ...

The authors further provided data supporting that the effects of nicotine on stem cell proliferation and tumor initiation were mediated by the Hippo-YAP/TAZ and Notch signal pathway ... leading to ...

A previous study reported that nicotine acts through the α2β4 nAChR to enhance Wnt production by Paneth cells ... "Nicotine enhances the stemness and tumorigenicity in intestinal stem cells via ...

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