With the latest injury to WR Brandon Aiyuk, the 49ers will have to find ways to win using their depth players.

The 49ers and wide receiver Brandon Aiyuk got the worst news on his injured right knee. According to a report from Fox Sports ...

Injuries always have a significant effect on the NFL season, but some teams are bearing the brunt of absences more than ...

On Monday, San Francisco 49ers wide receiver Deebo Samuel expressed his support for his injured teammate, Brandon Aiyuk. Head ...

A devastating wave of wide receiver injuries has put fantasy managers behind the 8 ball in Week 8. Here are some possible ...

Mike Florio and Devin McCourty react to the latest news out of San Francisco, discussing Brandon Aiyuk’s season-ending injury ...

The 49ers’ lone screen on Sunday went to rookie Jacob Cowing, who gained nine yards. It’s something he did well in college.

San Francisco 49ers face offensive challenges as injuries mount, leaving Purdy with limited options in loss to Kansas City ...

This week’s 49ers mailbag is stocked with questions (and answers) regarding their offensive shortcomings, fourth-quarter ...

When Ricky Pearsall finally made his debut for the San Francisco 49ers in Week 7, it felt like a special moment not just for fans of the red and gold but of the NFL, period. A first-round pick, fresh ...

The San Francisco 49ers faced some unfortunate injury news this past weekend, as Brandon Aiyuk suffered a torn ACL and a torn ...

The 49ers are among the Top-15 stop units in most advanced metrics, including sitting seventh in defensive DVOA at FTN. San ...