In this manuscript the authors established a novel three-dimensional culture system for stratified epithelia that allows epithelial cells to undergo epithelial-to-mesenchymal transition (EMT) and ...
Engineered immune cells called CAR-T cells are used in the treatment of cancer. Researchers from Uppsala University have now ...
Disparate pathogenic mechanisms complicate precision-medicine efforts to treat diffuse large B-cell lymphoma (DLBCL), the most common lymphoma diagnosis. Though potentially curable with frontline ...
A new imaging technique reveals ribosomes work together when translating mRNA, preventing slowdowns in protein production. This discovery challenges prior beliefs and could revolutionize our ...
Light and electron microscopy have distinct limitations. Light microscopy makes it difficult to resolve smaller and smaller features, and electron microscopy resolves small structures, but samples ...
Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...
Rigel Pharmaceuticals has enrolled the first subject in a Phase I trial of its oral spleen tyrosine kinase (SYK) inhibitor, fostamatinib, to treat sickle cell disease (SCD). The trial aims to assess ...
technology has opened new avenues for advancements in oncology and molecular pathology. Consequently, studies in renal cell carcinoma (RCC) have emerged, highlighting potential in histological subtype ...
Biologists had long believed that bringing order and organization to the chaos of molecules inside a cell depended on membrane-bound compartments called organelles, such as the mitochondria.
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