Endocytosis occurs when the cell membrane engulfs particles (dark blue) outside the cell, draws the contents in, and forms an intracellular vesicle called an endosome. This vesicle travels through ...

These include some obvious mechanical activities such as endocytosis, cell motility and membrane resealing, but also others, such as replication and transcription. Taking the motor proteins as an ...

Endocytosis and degradation of the membrane receptors in the lysosome controls the activation of intracellular signaling pathways, but the mechanisms that control the endocytosis itself are largely ...

Accumulation of fat molecules is detrimental to the cell. Researchers from the Yong Loo Lin School of Medicine, National ...

The protein Spns1 helps transport fat molecules out of lysosomes, preventing harmful buildup and offering insights for rare ...

But they didn’t know why. From prophase to anaphase, shallow clathrin-coated pits form at the plasma membrane, but the cell never internalizes them. Two main theories have tried to explain how ...

In our lab, we focus on clathrin-mediated endocytosis, the predominant route for membrane internalisation in most cells. In addition to its role in endocytosis, the clathrin machinery also forms ...

A new study shows how an anticancer drug triggers an “outside in” signal that gets it sucked into a cancer cell.

Functions of membrane microdomains on the endocytic pathway: integration of endocytosis and signalling We are interested ... for the uptake of a wide variety of cargo. Using live-cell microscopy we ...

Our goal is to unravel the early events that create the endosome/phagosome, a membrane-bound compartment that ... exploit it to enter and replicate within host cells. Additionally, disruptions in ...