Researchers at The Jackson Laboratory have discovered that certain genetic factors that predispose individuals to diabetes ...

Pacylex Pharmaceuticals Publishes a New Myristoylation Inhibitor Mechanism of Anti-Cancer Activity in Molecular Cancer Therapeutics ...

The endoplasmic reticulum (ER) is a compartment (organelle) in eukaryotic cells that consists of membrane sacs called cisternae. Because of the bound ribosomes, the 'rough' ER is the site of ...

Discover how diabetes risk genes impair cellular resilience, making cells more vulnerable to stress and damage, contributing ...

Study provides genome-wide insights into human islet stress responses and context-specific type 2 diabetes variant effects.

Gillham, SH, Cole, PL, Viggars, MR, Nolan, AH, Close, GL and Owens, DJ (2024) Comparative transcriptomics of broad-spectrum ...

Darier disease (DD) is a rare cutaneous disease caused by heterozygous mutations in the ATP2A2 gene, which encodes sarco/endoplasmic reticulum calcium ATPase isoform 2 (SERCA2).

ProJenX teamed with Unlearn to create digital twins of ALS patients as a placebo group in open-label extension of Phase 1 ...

The major protein components of myelin sheaths are synthesized in the endoplasmic reticulum (ER), and ER stress has been observed in patients with MS. Extracellular vesicles (EVs) have been shown to ...

Researchers meticulously examined the gametogenesis of budding yeast, a process involving meiosis and spore formation, using live imaging techniques. Their findings revealed that during sporulation, ...

Previously, the research group revealed that autophagosome formation takes place on the endoplasmic reticulum membrane in close proximity to mitochondria within cells. They also discovered that ...