Eledon Pharmaceuticals has a promising anti-CD40L antibody for organ rejection prevention in transplantation. Learn more ...

Fc receptors can combine with antigen-antibody complex and transfer information into cells. In a post-mortem study, microglial Fcγ receptors (CD64, CD64/HLA-DR) was elevated in the dorsal prefrontal ...

Immunological analyses suggested that the Fcγ receptor-dependent phagocytosis plays a predominant role in E6F6-mediated viral suppression. Molecular analyses suggested that E6F6 recognises an ...

Vaccine and natural immunity underlie the differences observed in Fcγ-receptor-binding (types I, IIa, and IIIa/b), IgG, IgM, and IgA production, and complement-fixing antibodies. Andrade ...

The latter consists of the phagocytosis of opsonized B-cells by neutrophils, monocytes and macrophages, which express the Fcγ Receptor. Moreover, RTX significantly decreases T-cell function, by ...

This medicine is designed to minimize binding to Fc-gamma (Fcγ) receptors on macrophages, helping the body’s immune cells detect, remain active longer and better fight tumors, while maintaining a ...

A sulfite allergy is caused by exposure to sulfur-based compounds naturally found in certain foods and used in certain food preservatives and additives. This can lead to allergy symptoms like wheezing ...

Compared with the other IgG subclasses, IgG4 has a negligible ability to activate the classic complement pathway, and its binding to Fcγ receptors is much lower than that of IgG1. IgG4 antibodies are ...

In ITP, Octagam 10% rapidly increases the platelet counts. The mechanism is believed to involve Fc receptor blockade, which prevents antibody-opsonized platelets from being destroyed by Fc ...

Study of 2.4 million participants reveals potential advantages for cardiometabolic and psychiatric conditions alongside increased risks of gastrointestinal and musculoskeletal issues Study ...

C3a and C5a act on mononuclear phagocytic cells and neutrophils to stimulate the respiratory burst and to enhance the expression of C3b receptors on these cells. As anaphylatoxins, C3a and C5a ...