A mouse study at Memorial Sloan Kettering Cancer Center has found that adding Nef, a protein from HIV, allows donor CAR T cells to avoid detection by the immune system while still attacking tumors.

The HIV-1 capsid is formed by a mesh of around 200 protein hexamers and pentamers, arranged similarly to a football. It is, however, not spherical, but shaped like a cone, with a narrow and a ...

Learn how the molecule EBC-46 could advance how HIV is treated and how researchers discovered it.

Among many of the viral offensive strategies, HIV-1 viral auxiliary proteins (Tat, Rev, Nef, Vif, Vpr and Vpu) play important roles in the host-pathogen interaction and thus have significant ...

HIV-1, like other viruses, lacks the machinery to produce its own proteins and must rely on the host cell to translate its genetic instructions. After entering host cells, it seizes control of the ...

HIV-1, like other viruses, lacks the machinery to produce its own proteins and must rely on the host cell to translate its genetic instructions. After entering host cells, it seizes control of the ...

some of the antibodies were not binding directly to the HIV viral antigen, but to immune molecules on its surface. "These antibodies actually make no direct contact with the viral protein," says ...

Positive HIV status as well as socioeconomic disadvantages, not breastfeeding, are associated with infant length and birth ...

Recent studies showed that a peptide, the protein transduction domain (PTD) from HIV Tat, could improve the distribution of cytoplasmic reporter proteins when administered systemically as fusion ...

rather than the HIV virus alone (gray). LA JOLLA, CA—Many vaccines work by introducing a protein to the body that resembles part of a virus. Ideally, the immune system will produce long-lasting ...

The scientists discovered that repetitive HIV vaccinations can lead the body ... “These antibodies actually make no direct contact with the viral protein,” said Sharidan Brown, a graduate ...

some of the antibodies were not binding directly to the HIV viral antigen, but to immune molecules on its surface. "These antibodies actually make no direct contact with the viral protein," says ...