Supercomputer simulations have revealed how changes in the shape of the HIV-1 capsid protein may help the virus squeeze its ...

Chelico's lab studies immune responses to HIV, particularly a family of proteins called APOBEC3 which cause mutations in the HIV virus. Her research and others' show that the virus uses a ...

An HIV drug was named “2024 Breakthrough of the Year” by Science Magazine. Biochemistry research from the University of Utah ...

A mouse study at Memorial Sloan Kettering Cancer Center has found that adding Nef, a protein from HIV, allows donor CAR T cells to avoid detection by the immune system while still attacking tumors.

Viruses, like those that cause COVID-19 or HIV, are formidable opponents once they invade our bodies. Antiviral treatments ...

Learn how the molecule EBC-46 could advance how HIV is treated and how researchers discovered it.

The HIV-1 capsid is formed by a mesh of around 200 protein hexamers and pentamers, arranged similarly to a football. It is, however, not spherical, but shaped like a cone, with a narrow and a ...

Recent studies showed that a peptide, the protein transduction domain (PTD) from HIV Tat, could improve the distribution of cytoplasmic reporter proteins when administered systemically as fusion ...

TAT is a nonstructural HIV protein of 86-101 amino acids that is made up of two exons. The largest part of the protein derives from the first exon and acts as a transacting nuclear regulatory ...

Analysis Reveals an Additional Mechanism Behind Statin Therapy's Heart-Related Benefits in People With HIV Dec. 11, 2024 — Investigators who previously found that a daily statin pill helps ...

CD8 + T cells can recognize and then kill HIV-infected cells following the presentation of fragments of viral proteins (epitopes) in the peptide-binding groove of MHC class I molecules on the ...