"Both the TET2 and ASXL1 genes can be mutated, individually or together, in clonal hematopoiesis, leukemia, and a premalignant form of cancer called myelodysplastic syndrome," says Dong.

"Both the TET2 and ASXL1 genes can be mutated, individually or together, in clonal hematopoiesis, leukemia, and a premalignant form of cancer called myelodysplastic syndrome," says Dong.

Normal hematopoiesis and immunity are best described ... and cell mediated immune responses are based. In contrast, leukemia, lymphoma and myeloma cells are monoclonal, with a relative morphologic ...

This valuable study presents a mouse gastruloid model that can be used to generate hematopoietic progenitors as well as leukemic cells. However, in its current form, the manuscript is inadequate ...

The formation of blood cellular components or hematopoiesis is a complex process regulated by genetic and epigenetic mechanisms. To ensure continuous blood cell production is necessary to preserve ...

Targeted Oncology provides news, videos, and reviews on the rapidly evolving world of targeted therapies and immunotherapy ...

Myelodysplastic syndromes (MDS) are marked by ineffective hematopoiesis and dysplasia, which elevate the risk of progression to acute myeloid leukemia (AML). The inflammatory environment in MDS alters ...