Antipsychotic drugs introduced over the past ... The older agent serving as a comparator was the high-potency (that is, with a high affinity for the dopamine receptor type 2) drug haloperidol ...

or oral typical antipsychotics (low, medium, or high potency) were compared on time to all-cause medication discontinuation for 1 year following initiation. Treatment group comparisons were based ...

For example, in a patient with preexisting parkinsonian symptoms, high-potency conventional antipsychotics may worsen the tremor and rigidity. However, high-potency antipsychotics might be ...