For example, prokaryotic organisms have ... producing multiple intracellular signals for every one receptor that is bound. Protein kinases such as PKA and PKC catalyze the transfer of phosphate ...

Receptors can bind an extracellular molecule (triangle), and this activates an intracellular process. Enzymes in the membrane can do the same thing they do in the cytoplasm of a cell: transform a ...

which are inhibitory cell surface receptors that can suppress antitumor immunity. Notably, intracellular checkpoint molecules within NK cells, such as FBP-1, EZH2, CIS, TIPE2, and HIF-1α ...