Less than a year ago, the 49ers and the Lions were the two best teams in the NFC. Now the Lions are on the verge of locking ...

Detroit Lions defensive coordinator Aaron Glenn called San Francisco 49ers TE George Kittle 'the best tight end in the game.' ...

The Detroit Lions visit the San Francisco 49ers on Monday at 8:15 p.m. ET, in a matchup featuring a pair of the best ...

Here is how to watch the rematch of last year's NFC Championship game between the Lions and 49ers on television: ...

John Lynch expects the Detroit Lions to seek revenge against the San Francisco 49ers on ESPN's "Monday Night Football" ...

Week 17 of "Monday Night Football" features the Detroit Lions and the San Francisco 49ers. Check out how to watch on ESPN.

The 49ers are eliminated from the playoffs. But don't tell Kittle or Samuel that, with both studs having two of their best ...

The Detroit Lions will know how meaningful their matchup with the San Francisco 49ers on Monday night will carry before they ...

The Detroit Lions and San Francisco 49ers met 11 months ago at Levi's Stadium with a trip to the Super Bowl on the line. San Francisco used a furious second half comeback to steal the NFC Championship ...

The Lions will face a 49ers offensive line that could be starting two tackles signed off practice squads this week ...

Find out what the San Francisco 49ers are saying as they prepare for their Week 17 matchup vs. the Detroit Lions.

The San Francisco 49ers are preparing for their Week 17 contest against the Detroit Lions on Monday at Levi's Stadium in ...