Background: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease ... often have significant adverse effects and may not fully control disease activity. Tofacitinib is an oral Janus ...

Accordingly, NIM-1324 is a prime candidate for a first-in-class oral therapeutic in the treatment ... from systemic lupus erythematosus (SLE) patients and provided protection from clinical disease ...

The treatment for the cutaneous lesions is strict sun avoidance and mid to low-potency topical steroids. Systemic steroids are not required for managing cutaneous lesions. Systemic antimalarial ...

Lupus (systemic lupus erythematosus) and multiple sclerosis can appear similar in many ways. Both lupus and MS are chronic autoimmune diseases. More than 100 different autoimmune diseases exist, with ...

Sept 30 (Reuters) - Kezar Life Sciences (KZR.O), opens new tab said on Monday it has paused a trial of its experimental drug for lupus to review safety data after four patients died in the mid ...

a kidney disease-related complication of systemic lupus erythematosus. Patients were dosed with either 30 mg of zetomipzomib, 60 mg of zetomipzomib or placebo and standard background therapy.

Other exclusions were women with moderate-severe hypertension at consultation (above 160/100 mm Hg) and comorbidities like diabetes mellitus, systemic lupus erythematosus, renal disease ...

The Chronic Cutaneous Lupus Erythematosus (CCLE) / Discoid Lupus Erythematosus ... Upon physical examination round, coin-shaped lesions are observed specifically butterfly rash over cheeks that can be ...

Systemic lupus erythematosus (SLE) and inflammatory bowel disease (IBD, a group of intestinal disorders that cause inflammation of the digestive tract) share a common set of microbiome features that ...

Seven weeks later, magnetic resonance imaging (MRI) of the abdomen and pelvis, performed after the administration of gadolinium, allowed for further characterization of the lesions. The lesion in ...