Research over the past decade has revealed multiple potential mechanisms by which dendritic cells contribute to the immunopathogenesis of systemic lupus erythematosus. Genetic abnormalities in ...

“Receiving this award was incredibly encouraging, as it reinforced that the work we are doing is important to understanding lupus pathogenesis. This grant gives me the opportunity to pursue a project ...

We will use this dataset to infer active biological pathways in these patients and develop novel dynamic models of Lupus pathogenesis." "The research group of Prof. Nir Hacohen from the Broad ...

Her research focuses on lupus outcomes as well as both translational projects which include studies investigating the pathogenesis of lupus and of neuropsychiatric lupus, and clinical trials of novel ...

How could these vaccines instigate a flare? “Type 1 interferon is a cytokine thought to be involved in lupus pathogenesis and flares,” Barbhaiya says. “There was some concern that the SARS ...

Arthritis Rheum 2010; 62: 211–21 CrossRef MEDLINE e1. Bertsias G, Cervera R, Boumpas D: Systemic lupus erythematosus: pathogenesis and clinical features. In: Bijlsma J (ed.): EULAR textbook on ...

People with lupus often need to use medicines to manage their symptoms. Although there are many oral medicines that treat lupus, some people with more severe symptoms may not get enough benefit ...

While the same can be said of many other diseases with diverse presentations—including lupus, multiple sclerosis, or psychiatric illnesses—the lack of a clear definition or disease pathway ...

To date, treatment with NIM-1324 has reduced the production of interferon alpha in human peripheral blood mononuclear cells (PBMCs) from systemic lupus erythematosus (SLE) patients and provided ...

Future Rheumatol. 2008;3(3):269-279. These phenotypic abnormalities, at least in part, appear to be intrinsic to the mDCs, as the addition of lupus serum to healthy control or lupus mDCs could not ...