Immune cells in the bone marrow microenvironment of AML patients are key in distinguishing a response to immunotherapy.

Here authors show that mutation-associated neoantigen-specific CD8+ tumor-infiltrating lymphocytes ... NKT cells, showing anti-tumor activity in preclinical models of bone marrow-resident myeloid ...

Furthermore, HEVs in the paracortex can often mediate the recruitment of cells other than lymphocytes, such as antigen-presenting cells that have accumulated antigen in the periphery. The ...

But to this day, there's never been a molecule, a fusion protein, that rescues lymphocytes, the NK cells and T cells, which are the key cells for killing cancer and generating memory. For the first ...

A type of aggressive, treatment-resistant brain tumor has a distinct population of immune cells that support its growth, ...

A type of aggressive, treatment-resistant brain tumor has a distinct population of immune cells that support its growth, according to new research led by investigators at the Johns Hopkins Kimmel ...

Megakaryocytes form a three-dimensional (3D) cage composed of laminin and collagen IV connected to the basement membrane surrounding them. This microarchitecture stabilizes megakaryocytes within their ...

4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in ... of acute myeloid leukemia and ...

Families are stronger together, and so are the best family cell phone plans in my experience. The plans that I find the most appealing are the ones that add significant discounts as you add more ...

Many cells in multicellular organisms are specialised. They have specific roles in the organism of which they are part. Their structure is adapted to their function. They are often grouped ...

This had never happened before. There is a remarkable story behind these cells; it's more than half a century old, but still relevant and current. Dr Maninder Ahluwalia, senior lecturer in ...

Lenovo’s Legion Go S was one of the worst-kept secrets for CES 2025, but now we don’t need to pretend anymore, as we’ve not only seen it in the flesh, but we’ve had enough time to give it ...