1 ALS patients in a TLS may exhibit severe, widespread involvement of the cerebral ... to use MRI to visualise chronological changes in sporadic amyotrophic lateral sclerosis (ALS) in a totally locked ...

To define the temporal evolution of intrinsic tissue damage and atrophy in the cervical cord and the brain portion of the corticospinal tracts (CST) from patients with amyotrophic lateral sclerosis ...

OBJECTIVE To investigate patients with an unusual type of muscular atrophy confined to the upper limbs (proximally ... typical neurogenic changes in the limbs of all patients. Cervical MRI disclosed ...

In this review, we will summarise the proposed mechanisms contributing to brain atrophy in patients with multiple sclerosis. We will critically discuss the wide range of MRI-based methods used to ...

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that remains incurable, despite decades of basic and clinical research. Key stakeholders—including the US National ...

Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disease characterized by loss of motor neurons in the brain and spinal cord. Mutations in the gene encoding superoxide ...

ALS (amyotrophic lateral sclerosis) is also known as Lou Gehrig’s disease after the New York Yankees player who was diagnosed with it in 1939. It is a group of conditions that affect ...

The concurrence of multiple sclerosis (MS) and amyotrophic lateral sclerosis (ALS) is exceedingly rare and the pathological features have not been examined extensively. Here we describe the key ...

Amyotrophic lateral sclerosis (ALS) is also known as motor neuron disease ... Your doctor may also decide that you need more testing after this, such as an MRI or a genetic test. Our multidisciplinary ...