To enable antibody discovery, membrane protein scientists at TetraGenetics encapsulate and stabilize purified protein in an artificial bilayer with immune-stimulating molecules to generate ...

Many drug and antibody discovery pathways focus on intricately folded cell membrane proteins: when molecules of a drug ...

Chiome’s monoclonal antibody discovery engine also includes technologies to prepare soluble proteins and membrane proteins for research, and create antibody-based multi-specific modalities.

Antibody development ... but some proteins are very difficult to reproduce with their three-dimensional shape intact. For example, they may normally loop in and out of membranes, but you've removed ...

Membrane proteins are key targets for therapeutic intervention using antibody biologics. Over 60% of FDA-approved drugs act on these proteins. Studying them is challenging because the proteins ...

Get Instant Summarized Text (Gist) A specific antibody has been identified that targets age-related damage to proteins in lung tissue, potentially curing diseases like pulmonary fibrosis. This ...

Jimmy D. Gollihar, Ph.D. is the head of the Antibody Discovery & Accelerated Protein Therapeutics (ADAPT) laboratory at the Houston Methodist Research Institute. The ADAPT lab is a modern ...

A new storage technique can keep protein-based drugs and vaccines stable without keeping them cold. The discovery ... monoclonal antibodies and viral vaccines. "Over 80% of biologic drugs and ...

Many vaccines work by introducing a protein to the body that resembles part of a virus. Ideally, the immune system will produce long-lasting antibodies recognizing that specific virus, thereby ...

Tissue processing advance can label proteins at the level of individual cells across whole, intact rodent brains and other large samples just as fast and uniformly as in dissociated single cells.