Messenger RNA (mRNA) serves as a blueprint for proteins. When mRNA is no longer needed, it must be degraded. Director Elena ...

"RNA decay rates are one of the fundamental parameters governing gene expression. Our findings have implications for almost all studies dealing with the adaptation of the transcriptome, the total ...

Dr. Lynne Maquat, a mechanistic biochemist and the director of the University of Rochester Center for RNA Biology, was ...

Messenger RNA–based therapeutics and vaccines are the new hope in the fight against incurable diseases. A commonly used strategy in the development of messenger RNA (mRNA) medicine is based on the ...

NEXT is then recruited through a direct interaction between ZCCHC8 and ZC3H4, which lead to RNA degradation by the RNA exosome ...

It’s the rarest particle decay ever discovered. Scientists have clinched the case for a special type of decay of subatomic particles called kaons. Further study of the rare decay could reveal a ...

Lynne E. Maquat, PhD, director of the Center for RNA Biology at the University of Rochester, has been awarded the 2024 Albany ...

Scientists have discovered an ultra-rare particle decay process, opening a new path to find physics beyond our understanding of how the building blocks of matter interact. Scientists at CERN have ...

The structure of a human exosome–ribosome supercomplex reveals the mechanisms behind the formation of active cytoplasmic exosomes and their role in co-translational RNA decay. The prokaryotic ...

Long known as a messenger within cells, RNA is increasingly seen as life’s molecular communication system — even between organisms widely separated by evolution. For a molecule of RNA, the world is a ...

The chemical structure of uracil, showing its single-ring pyrimidine structure. Uracil forms hydrogen bonds with adenine in RNA, contributing to the molecule's structure and function. (Image: Public ...