Messenger RNA–based therapeutics and vaccines are the new hope in the fight against incurable diseases. A commonly used strategy in the development of messenger RNA (mRNA) medicine is based on the ...

Dr. Lynne Maquat, a mechanistic biochemist and the director of the University of Rochester Center for RNA Biology, was ...

Messenger RNA (mRNA) serves as a blueprint for proteins. When mRNA is no longer needed, it must be degraded. Director Elena ...

Lynne E. Maquat, PhD, director of the Center for RNA Biology at the University of Rochester, has been awarded the 2024 Albany ...

RNA was extracted and equal amounts of total RNA were loaded ... Transcription was then blocked by adding thiolutin and mRNA decay assay was performed (see Methods). (B) Sfp1 stabilizes CRAC+ mRNAs ...

Options are wasting assets, which means their value declines over time—a phenomenon known as time decay. A number of factors influence the time decay of an option, one of the most important ...

RNA stability, important for eukaryotic gene expression ... To clarify the role of deadenylation in mRNA decay, we first modeled mRNA poly(A) tail kinetics and mRNA stability in yeast. Independent of ...

Geneva, 25 September 2024. At a seminar held at CERN this week, the NA62 collaboration reported the unequivocal confirmation of the ultra-rare decay of a positively charged kaon into a positively ...

It’s the rarest particle decay ever discovered. Scientists have clinched the case for a special type of decay of subatomic particles called kaons. Further study of the rare decay could reveal a ...

Scientists have discovered an ultra-rare particle decay process, opening a new path to find physics beyond our understanding of how the building blocks of matter interact. Scientists at CERN have ...

The structure of a human exosome–ribosome supercomplex reveals the mechanisms behind the formation of active cytoplasmic exosomes and their role in co-translational RNA decay. The prokaryotic ...