NF-κB activation is important in the development of the inflammation observed in UC. The SCFA (short chain fatty acid) butyrate has demonstrated anti-inflammatory effects that are associated with ...

Dextran sodium sulphate-induced colitis experiments in mice were used to evaluate effects of identified metabolites. In vitro, ex vivo and in vivo experiments were used to decipher mechanisms involved ...

We provide a scoping overview of the most studied diseases mechanisms associated with the induction or prevention of Inflammatory Bowel Disease in rodent models relevant to Crohn’s Disease and ...

The prebiotic effect of a given PS therefore depends on its ability to stimulate beneficial bacteria exerting directly or indirectly, through the production of SCFA, beneficial effects for health, or ...

Correspondence to Dr Hein M Tun, HKU-Pasteur Research Pole, School of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China; heinmtun{at}hku.hk; Professor Francis ...