It seems like Adrien Brody can't stay within his lines! In May 2003, The Grand Budapest Hotel star hosted an episode of the Emmy-winning 'Saturday Night Live'. During the May 10 episode, Brody went ...

Scroll through the sprawling list of musical guests that have graced “Saturday Night Live” in the show’s 50-year history and you’ll see an impossible breadth of pop culture passing through a pinhole.

As the show gears up to celebrate its milestone, here are 12 moments over the past five decades when the show didn't just reflect pop culture — it drove it.