The EMBO Journal3d
Type-2 innate signals are dispensable for skeletal muscle regeneration and pathology linked to Duchenne muscular dystrophy
Contrary to prior data, this study shows that neither eosinophils nor STAT6-mediated IL-4/IL-13 signaling contribute ...
pharmaphorum2d
FDA says no to Astellas' geographic atrophy drug
Astellas has suffered another major setback with geographic atrophy (GA) treatment Izervay, this time in the US. The company has received a complete response letter (CRL) from the FDA for a ...
Nature3d
Guidelines for the prenatal diagnosis of fetal skeletal dysplasias
Diagnosis of prenatal-onset skeletal dysplasias can be accomplished by ultrasound evaluation and confirmed by both molecular testing using invasive procedures and postdelivery radiographs and ...
Medscape4d
Lactational Atrophic Vaginitis
The management of atrophic vaginitis may include self-help measures, estrogen replacement, and botanical therapies, as well as education. Self-help measures include the use of water-based vaginal ...
Science Daily4d
Bone and Spine News
Oct. 30, 2024 — A new study of human skeletal remains from the wreck of the 16th century English warship Mary Rose suggests that whether a person is right- versus left-handed may influence how ...
Frontiers4d
Enhanced Nerve Regeneration by Bionic Conductive Nerve Scaffold Under Electrical Stimulation
At the 8 and 12th weeks after implantation, the bilateral gastrocnemius muscles were completely removed from the medial and lateral femoral condyles to the calcaneal tubercle to calculate the atrophy ...
ahajournals.org4d
Current Diagnostic and Treatment Strategies for Specific Dilated Cardiomyopathies: A Scientific Statement From the American Heart Association
The term dilated cardiomyopathy (DCM) refers to a spectrum of heterogeneous myocardial disorders that are characterized by ventricular dilation and depressed myocardial performance in the absence of ...
Frontiers4d
Systemic inflammation and the brain: novel roles of genetic, molecular, and environmental cues as drivers of neurodegeneration
The nervous and immune systems have evolved in parallel from the early bilaterians, in which innate immunity and a central nervous system (CNS) coexisted for the first time, to jawed vertebrates and ...
BMJ4d
Urinary dysfunction and orthostatic hypotension in multiple system atrophy: which is the more common and earlier manifestation?
med.m.chiba-u.ac.jp OBJECTIVES Urinary dysfunction and orthostatic hypotension are the prominent autonomic features in multiple system atrophy (MSA). A detailed questionnaire was given and autonomic ...