Anticoagulation variability is highest in the first few months after initiation of warfarin. In one study, only 29% of patient days were within the recommended INR range of 3-4.5 in the first 3 ...

I.V. warfarin was chosen initially based ... (to be administered by a home health care nurse) until the INR was in the therapeutic range. Daily, long-term, low-molecular-weight heparin (LMWH ...

Currently, anticoagulation with warfarin is generally prescribed ... spent less time in the international normalized ratio [INR] target range) and a much higher risk of excessive anticoagulation ...