Background Colorectal cancer (CRC) is a common and preventable disease for which screening rates by colonoscopy remain unacceptably low. Our primary objective was to develop and validate a clinical ...

In an attempt to study the relative toxicity of anthraquinonic laxatives on intestinal mucosa, we compared in mice the effects of fruit pulp containing sennosides A and B with those of a free ...

2 Center for Functional Gastrointestinal and Motility Disorders, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA 3 Translational Research Center for Gastrointestinal ...

Correspondence to Dr Citadel J Cabasag, Cancer Surveillance Branch, International Agency for Research on Cancer, Lyon, France; cabasagc{at}fellows.iarc.fr We read with interest the commentary by ...

Correspondence to Dr Feng Sun, Department of Epidemiology and Biostatistics, Peking University Health Science Center, Beijing 100191, China; sunfeng{at}bjmu.edu.cn SS and QY contributed equally.

Objective Cancer-associated fibroblasts (CAFs) influence the tumour microenvironment and tumour growth. However, the role of CAFs in colorectal cancer (CRC) development is incompletely understood.

1 Department of Gastroenterology, Barts and The London NHS Trust, London, UK 2 Upper Gastrointestinal Physiology Unit, Barts and the London School of Medicine and Dentistry, London, UK 3 Department of ...

1 Dalhousie Inflammation Group and Department of Pediatrics, and Department of Microbiology and Immunology, Dalhousie University, Halifax, Nova Scotia, Canada 2 Dalhousie Inflammation Group and ...

Histopathology Unit, Imperial Cancer Research Fund, Royal College of Surgeons, London. Diet is of fundamental importance in the healthy functioning of alimentary epithelium, or during the disease ...

1 Mech-Sense, Department of Gastroenterology, Aalborg University Hospital, Aalborg, Denmark 2 Center for Sensory-Motor Interactions, Department of Health Science and Technology, Aalborg University, ...

Dr A L Warshaw, W Gerald Austen Professor of Surgery, Surgeon-in-Chief, Massachusetts General Hospital, Boston, Massachusetts 02114, USA. Background—Ectopic protease activation, microcirculatory ...

University of Technology of Compiègne, UMR CNRS 6600 – Biomechanics and Bioengineering, Compiègne, France Correspondence to Dr C Legallais, UTC, UMR CNRS 6600 Biomechanics and Bioengineering, BP 20529 ...